⚠️ FOR RESEARCH AND EDUCATIONAL PURPOSES ONLY
This calculator demonstrates theoretical pharmacokinetic modeling based on published half-life data. It is not intended as medical advice or instructions for human use. Retatrutide is an investigational compound not approved for human consumption.
Pharmacokinetic Modeling Calculator
Educational tool for understanding theoretical drug accumulation and steady-state concepts
Dosing Schedule
Current Level
1.8mg
0% of steady state
Steady State
4.0mg
~2x final dose (2.0mg)
To Steady State
4
weeks to final steady state
Treatment Period - Level Projection
Note: The chart shows accumulated compound levels, including residual amounts from previous doses. Each injection adds to existing levels rather than replacing them.
Key Insights
Peak Levels
Occur approximately 48-72 hours after injection. Maximum appetite suppression typically experienced during this window.
Trough Levels
Lowest levels occur just before your next injection. Some appetite return is normal during this period.
Steady State
Reached after 4-5 weeks on your final dose. Blood levels stabilize at approximately 2x your weekly dose due to accumulation.
Dose Escalation
Gradual dose increases help minimize side effects while building tolerance. Use Advanced Mode to model your escalation schedule.
Retatrutide Pharmacokinetics Explained
The calculator uses established pharmacokinetic principles to model drug accumulation:
Key Parameters:
- Half-life: ~168 hours (7 days)
- Dosing interval: Weekly (168 hours)
- Steady state: Reached after ~5 half-lives
- Accumulation factor: ~2x the single dose
With weekly dosing at the same interval as the half-life, Retatrutide levels will accumulate to approximately double the single-dose level at steady state.